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lumacaftor/ivacaftor will lessen the extent or result of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers reduces plasma focus of abemaciclib and its metabolites.When you've got an an infection, or should you feel that you might be